DeepMind has released AlphaGenome, a large-scale AI model that processes up to one million DNA base-pairs to predict thousands of molecular properties, such as gene expression, splicing, chromatin accessibility, and protein binding, across diverse tissues and cell types.
It excels on 24 of 26 benchmark tasks, including non-coding (“dark matter”) regions, and outperforms previous models like Enformer.
This unified model helps researchers rapidly assess the impact of genetic variants, accelerating discovery in disease mechanisms and synthetic biology. Available now via an API preview for non-commercial research.
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