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How can you prevent AI failures in healthcare?

Siddharth Menon

June 20, 2025
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AI is quietly becoming one of the most transformative forces in modern healthcare. What began as experimental models in research labs is now guiding clinical decisions, streamlining operations, and helping predict patient outcomes with remarkable accuracy. From diagnostics to drug discovery, artificial intelligence is a core enabler of better, faster, and more personalized care. Yet, behind the hype lies a harsh truth: there are a lot of AI failures in healthcare deployments.

So... why does this happen? And what does it take to build AI systems that actually deliver in real-world clinical settings?

Why do AI failures in healthcare happen?

Despite breakthroughs in language models, image recognition, and decision systems, many AI healthcare tools fail to create impact where it matters: at the bedside, in the EHR, and across patient journeys.

Here’s why:

1. Poor data quality

Most healthcare data is:

  • Unstructured (clinical notes, PDFs, imaging)
  • Incomplete or inconsistent across systems
  • Stored in siloed, legacy platforms

AI models trained on bad or limited data tend to hallucinate or underperform. In real-world settings, clean, multi-modal, labelled data is everything.

2. Lack of diversity in training sets

AI trained on narrow or homogeneous datasets often fails when deployed in different populations. For example:

  • Skin disease classifiers trained on light-skinned patients often underperform on darker skin tones
  • Clinical AI tools built for one hospital’s workflow can’t generalize to another’s

3. Black-box decision making

Physicians won’t use AI they don’t trust. Most models today still operate as “black boxes”, offering little to no explanation of why a certain recommendation was made.

This erodes clinical trust and slows adoption.

4. Poor workflow fit

AI solutions that sit outside the physician’s workflow get ignored. Clinicians hate additional logins, switching tabs, or extra training when they would rather work with patients. What works in a lab demo doesn’t always work in a busy ER.

5. Missing regulatory alignment

From HIPAA compliance to clinical validation under standards like TRIPOD-AI and CONSORT-AI, many AI tools are not ready for regulated healthcare environments.

How to avoid AI failures in healthcare?

While most AI startups get stuck at the pilot phase, GoML builds and deploys AI that works in production for hospitals, care teams, and patient workflows.

Here’s how:

1. Multi-modal, clean data pipelines

The quality of training data directly impacts outcomes. Ensure your gen AI implementations ingest and process:

  • Structured EHR data (labs, vitals, meds)
  • Unstructured notes and discharge summaries
  • Radiology and imaging files
  • Audio transcripts and clinical conversations

This multi-layered input makes the AI more contextual, accurate, and adaptable.

2. Human-in-the-loop design

Include clinicians in the loop during model training, evaluation, and deployment. This is because healthcare is a high-stakes vertical.

This ensures:

  • Clinical relevance
  • Ongoing validation
  • Real-world alignment

3. Explainability and trust

Avoids black-box behavior. To work around this, ensure your AI output includes:

  • Confidence scores
  • Cited evidence (via RAG)
  • Transparent logic paths

Physicians can ask why - and get a clear answer.

4. Embedded workflow integration

Depending on the specific use-case, your AI agent must be designed to integrate directly into:

  • Hospital dashboards
  • EMR platforms
  • Clinical copilot interfaces

No extra login. No tab-switching. Just usable AI where it’s needed.

5. Compliant and validated systems

Deployments must always be aligned with the necessary compliance standards, based on the specific use case. This ensures both safety and long-term performance.

Healthcare AI implementations than did not fail

Healthcare continues to emerge as one of the most promising domains for applied generative AI. Across hospitals and care systems, AI copilots and agents are beginning to demonstrate real-world value - not just in pilots, but in live clinical environments.

The following examples illustrate how AI, when thoughtfully deployed, can overcome common failure points and drive measurable outcomes:

GoML deployments

Patient diagnosis assistant

Client: Atria Health

Challenge: Triage delays due to manual EHR reviews

Solution: Multi-modal AI pipeline for real-time diagnosis

Outcome: Onboarded in 1 day; helped save a 9-year-old’s life

Clinical copilot for patient health summary

Client: Max Healthcare

Challenge: Doctors lacked unified patient insight across visits

Solution: RAG-powered copilot with patient timelines + trends

Outcome: Improved diagnostic quality and faster clinical decision-making

Chronic care navigator  

Partner: Confidential  

Challenge: Fragmented data across long-term care journeys

Solution: Predictive assistant for chronic and elderly care

Outcome: Pilot launching Q3 2025

Other industry examples

Mayo Clinic – Clinical note summarization

Challenge: Manual review of lengthy patient notes

Solution: Google Health’s AI models for summarizing physician notes

Outcome: Reduced documentation time, improved clinician satisfaction

GE Healthcare – Imaging workflow optimization

Challenge: Radiologists overloaded with manual tasks

Solution: AI-powered prioritization of abnormal scans

Outcome: Faster triage of critical cases, better use of radiologist time

To avoid AI failures in healthcare, we don’t just need smarter models.

We need:

  • Better integrations
  • Greater transparency
  • Stronger trust
  • Measurable outcomes

That’s what we focus on at GoML - building generative AI solutions that don’t just stay in pilot mode. Our AI copilots are live, embedded in real workflows, and already driving meaningful outcomes in healthcare.